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Despite these findings, Tesamorelin did not significantly affect liver enzymes such as alanine aminotransferase (ALT) and gamma-glutamyl transferase (GGT) overall

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Ornellas et al ., 2011, "Naltrexone SR/Bupropion SR (Contrave): A new approach to weight loss in obese adults"

Based on these data, the FDA approved tesamorelin (marketed as EGRIFTA) for the reduction of excess abdominal fat in HIVassociated lipodystrophy, not as a general weightloss drug for the wider population. Tesamorelin Risks and Considerations Like all hormonemodulating therapies, tesamorelin carries potential risks, including fluid retention, joint pain, injectionsite reactions, and effects on glucose metabolism in susceptible patients